1-Naphthalenepropanoic Acid
5690-03-9
198.2
C13H10O2
DMF, DMSO, Ethanol
-20°C
Splitomicin is an Sirt1 inhibitor. Potent inhibitor of yeast NAD-dependent histone deacetylase Sir2p (IC= 60 M). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
